Epigenomic Disruption of Cardiovascular Care
نویسندگان
چکیده
منابع مشابه
Detection of Epigenomic Network Community
In this paper we propose network methodology to infer prognostic cancer biomarkers based on the epigenetic pattern DNA methylation. Epigenetic processes such as DNA methylation reflect environmental risk factors, and are increasingly recognised for their fundamental role in diseases such as cancer. DNA methylation is a gene-regulatory pattern, and hence provides a means by which to assess genom...
متن کاملSnapShot: Epigenomic Assays
This SnapShot depicts key sequencing-based methods used in the analysis of epigenomes, including (1)bisulfite sequencing, (2) chromatin immunoprecipiation sequencing, (3) determination of open chromatin, and (4) 3D chromatin capture.
متن کاملDisruption of normal circadian rhythms and cardiovascular events
The intrinsic properties of the heart and the vascular tree exhibit marked oscillations over 24 h. Diurnal variations in the response of the cardiovascular system to environmental stimuli are mediated by the complex interplay of extracellular (ie, neurohumoral factors) and intracellular (ie, circadian clock) influences. The intracellular circadian clock comprises a series of transcriptional mod...
متن کاملThe Epigenomic Landscape of Prokaryotes.
DNA methylation acts in concert with restriction enzymes to protect the integrity of prokaryotic genomes. Studies in a limited number of organisms suggest that methylation also contributes to prokaryotic genome regulation, but the prevalence and properties of such non-restriction-associated methylation systems remain poorly understood. Here, we used single molecule, real-time sequencing to map ...
متن کاملDisruption in the diabetic device care market
As diabetes mellitus (DM) has approached pandemic proportions, the pressure for effective glycemic management is mounting. The starting point for managing and living well with DM involves early diagnosis and monitoring blood glucose levels. Therefore, self-monitoring of blood glucose (SMBG) can help patients maintain their blood glucose levels within the appropriate range. The general principle...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Circulation Research
سال: 2017
ISSN: 0009-7330,1524-4571
DOI: 10.1161/circresaha.117.311072